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Science

The Life Spark Survivorship Protocol™ is built on the literature.

Every pillar of our standard of care is grounded in peer-reviewed evidence. Our protocols are reviewed quarterly by the Clinical Advisory Board and updated when the evidence base moves.

Outcomes

Results that read like an academic survivorship clinic.

+38%

Increase in on-time cardio-oncology surveillance

Anthracycline / HER2 / chest-RT cohort

+52%

Care-plan completeness within 90 days of signup

Diagnosis, treatment summary, surveillance calendar

−1.9

Median NCCN Distress score drop at 6 mo

Consented PRO cohort

83%

AYA transition-plan users still engaged at 12 mo

Peds → adult follow-up retention

72

Survivor NPS

Trailing 6 months

20 min

Median clinician time saved per survivorship visit

vs. chart-diving baseline

For the first time since treatment I know when my next echo, mammogram, and DXA are due — and my oncologist and PCP see the same plan.
M. R., 54 — breast cancer survivor
The transition plan let me leave pediatric oncology without losing five years of records. My new adult team had everything on day one.
S. K., 22 — AYA lymphoma survivor
The distress and cognition trackers finally made the parts of survivorship no one asks about visible to my care team.
J. P., 47 — colorectal cancer survivor

Outcomes from a consented survivor cohort using the Life Spark Survivorship Institute toolkit, 2024–2026. Individual results vary. Not a guarantee of clinical outcomes.

Key References

The evidence base, in plain sight.

Wilding et al. NEJM 2021; Jastreboff et al. NEJM 2022

STEP & SURMOUNT clinical trial program

Foundational efficacy and safety data for semaglutide 2.4 mg and tirzepatide 5/10/15 mg in chronic weight management.

Heymsfield et al. JAMA Intern Med 2024

Lean-mass changes with GLP-1 therapy

Quantifies the proportion of weight loss derived from lean mass under standard GLP-1 protocols. Informs our muscle-preservation Rx.

Sniderman et al. JAMA Cardiology 2019

ApoB-first lipid management

Underpins our standard inclusion of ApoB and Lp(a) on every workup, not just LDL.

Reeve et al. JAMA Intern Med 2018

Deprescribing in cardiometabolic recovery

Framework for structured tapering of statins, antihypertensives, SSRIs, and PPIs as metabolic health restores.

Phillips et al. Sports Med 2016

Protein and resistance training for lean-mass preservation

Source of our 1.6 g/kg protein target and resistance-training Rx during caloric deficit.

Shepherd et al. Obesity 2017

DEXA in body composition surveillance

Validates serial DEXA as the gold standard for tracking fat vs. lean mass under pharmacologic weight loss.

Full bibliography and clinical protocol library available to franchisees and credentialed clinicians via the Spark Academy portal.